Senior Scientist I, Cancer Genomics, Clinical Biomarker Development Job at Revolution Medicines, Redwood City, CA

  • Revolution Medicines
  • Redwood City, CA

Job Description

Revolution Medicines seeks a Senior Scientist I in Cancer Genomics to develop biomarkers and computational strategies for RAS(ON) inhibitor clinical programs. The role involves applying advanced genomics analyses to clinical samples across Phase I-III studies within a collaborative translational medicine team.

Responsibilities

  • Apply advanced genomics analytics to clinical biomarker data supporting R&D initiatives
  • Integrate multi-omics datasets to analyze disease biology, resistance mechanisms, and drug response prediction
  • Partner across functional teams to deliver biomarker analyses and actionable recommendations
  • Communicate scientific findings to diverse audiences through publications and presentations

Requirements

  • Ph.D. in Cancer Genomics, Genetics, Computational Biology, Bioinformatics, or related field
  • 2-8 years post-PhD experience analyzing cancer genomics data in biotech, pharma, or diagnostics
  • Strong cancer biology knowledge with RAS/MAPK signaling expertise in pancreatic, lung, or colorectal cancers
  • Proficiency in R and/or Python with version control (git) expertise
  • Linux and cloud computing experience including HPC clusters and NGS workflow development
  • Hands-on experience with ctDNA and liquid biopsy data analysis from blood samples
  • Expertise in tumor tissue DNA sequencing analysis (gene panel, whole-exome, whole-genome)

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